Direct conversion of cardiac fibroblasts into induced cardiomyocytes (iCMs) by forced expression of defined factors holds great potential for regenerative medicine by offering an alternative strategy for treatment of heart disease.Successful iCM conversion can be achieved by minimally using three transcription factors, Mef2c (M), Gata4(G), and Tbx5
We highlight the importance of island research that aims to achieve sustainability transitions.All too often, developmental priorities are largely defined by economic policy imperatives, and island research either ignores or masks 2006 nissan altima radio such normative connotations.This article reports on ten years of transdisciplinary socioecolog
Mutations in TRPC6 are a cause of autosomal dominant focal segmental glomerulosclerosis in humans.Many of these mutations are known to have a gain-of-function effect on the non-specific cation channel function of TRPC6.In vitro studies have suggested these mutations affect several signaling pathways, but in vivo studies have largely compared wild-t
The present Atlas contains a detailed study, based in scanning electron microscopy (SEM) observations, of living coccolithophores from NW Mediterranean waters.The study contains 103 figures with 411 micrographs, truvisionhealthftp.com which correspond to 168 coccolithophores (including different taxonomic and morphotypic entities).The figured speci